Call for Abstract
4th Glycobiology World Congress, will be organized around the theme “Glycobiology: The Study of Sweet Life”
Glycobiology 2018 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Glycobiology 2018
Submit your abstract to any of the mentioned tracks.
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Glycobiology and Glycochemistry are the two main intertwined areas of Glycosciences, dealing with various aspects of glycans, including carbohydrate structure, biochemistry, biological functions and applications. This is necessary in order to sustain and advance the identification of key glycobiological aspects and the application of glycans and glyco-engineering strategies in the design of novel therapies to improve human health. The glycans (carbohydrates) form a diverse group of biomolecules which play active parts in most physiological processes. The field of structural glycobiology concerns the structures of the glycans themselves, the proteins which interact with them and the nature of the interactions between the two. Drug targeting is important for our understanding of human health and disease, and for development of new therapeutic strategies.
- Track 1-1Glycoconjugate synthesis
- Track 1-2Glycans in human physiological mechanisms
- Track 1-3Carbohydrate Sythesis
- Track 1-4Host-pathogen interactions
- Track 1-5Glyconutrients
- Track 1-6Microbial glycobiology
Genomics is the study of the genome in contrast to genetics which refers to the study of genes and their roles in inheritance. Genomics can be considered a discipline in genetics. It applies recombinant DNA, DNA sequencing methods and bioinformatics tools to sequence, assemble and analyze the function and structure of genomes with the complete set of DNA within a single cell of an organism. Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping.
- Track 2-1Frontiers of metabolomics research
- Track 2-2Metabolomics in precision medicine
- Track 2-3Clinical metabolomics & lipidomics
- Track 2-4Cancer therapeutic approaches
- Track 2-5Genome analysis
- Track 2-6Genomic medicine
- Track 2-7Epigenomics
Glycomedicine plays major role in cell-cell adhesion i.e. a mechanism employed by cells of the immune system via sugar-binding proteins called lectins, which recognize specific carbohydrate moieties. Glycans (carbohydrate oligomers) are the so-called “building blocks” of carbohydrates, nucleic acids, proteins and lipids play major roles in many biological phenomena as well as in various pathophysiological processes. Many scientists in other fields of research have now realized that glycosylation, i.e. the addition of glycans to a protein backbone, is the most abundant post translational modification reactions and is an important field of research and sometimes they require a glycobiology and/or glycochemistry approach to be used.
- Track 3-1Congenital disorders of glycosylation (CDG)
- Track 3-2Cardiovascular diseases
- Track 3-3Cancer biomarkers
- Track 3-4Cancer associated coagulopathies
- Track 3-5Transfusion medicine
- Track 3-6Cardiac arrest
- Track 3-7Glycomedicine
Cancer is caused when cells within the body accumulate genetic mutations and start to grow in an uncontrolled manner. Understanding how cancer develops and progresses including how glycan mutations drive the growth and spread of cancer cells and how tumours interact with their surrounding environment is vital for the discovery of new targeted cancer treatments. Researchers are working to understand the process by which cancer spreads known as metastasis with the aim of developing new treatments that prevent cancer spread or target metastatic tumours. Scientists believe the glycolipid complexity arises in part because tumours develop through a process of evolution by natural selection just as species of animals and plants have done.
- Track 4-13D structure determination
- Track 4-2Drug designing
- Track 4-3Molecular modelling and protein dynamics
- Track 4-4Sequencing methods
- Track 4-5Cancer biomarkers
- Track 4-6Cancer genes and pathways
- Track 4-7Cancer risk and diagnosis
- Track 4-8Chemotherapy and oncogenesis
Mass spectrometry (MS) based proteomics allows the sensitive and accurate quantification of almost complete proteomes of complex biological fluids and tissues. At the moment, however, the routinely usage of MS-based proteomics is prevented and complicated by the very complex work flow comprising sample preparation, chromatography, MS measurement followed by data processing and evaluation. The new technologies, products and assays developed by Precision Proteomics could help enabling and establishing mass spectrometry (MS) - based proteomics in academic and pharmaceutical research as well as in clinical diagnostics.
- Track 5-1Mass spectrometry in proteome research
- Track 5-2Mass spectrometry imaging
- Track 5-3New approaches in mass spectrometry
- Track 5-4Recent advances in mass spectrometry
- Track 5-5Mass spectrometry in drug discovery
- Track 5-6Mass spectrometry based proteomics
- Track 5-7Applications of mass spectrometry
- Track 5-8Clinical application of mass spectrometry
Glycomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods and bioinformatics to sequence, assemble and analyze the function and structure of glycans along with the genomes. Transcriptomics is a relatively young branch of omics science concerned with the systematic study of the chemical products or metabolites that cells and organisms generate. Indeed, most human metabolomic studies published today, even those exploiting the latest and most sensitive LC-MS/MS technologies, typically succeed in identifying or characterizing fewer than 100 compounds. This corresponds to less than 1% of the known human metabolome.
- Track 6-1Gene expression profiling
- Track 6-2Transcriptome analysis
- Track 6-3Next generation sequencing (NGS) technologies
- Track 6-4Whole genome sequencing
- Track 6-5Glycan synthesis
- Track 6-6Cancer genome biology
Glycans are components of many bio-therapeutic agents, ranging from natural products to molecules based on rational design to recombinant glycoproteins. The glycan components of these agents can be important determinants of their biological activity and therapeutic efficacy. Biochemistry and Glycobiology involves a multidisciplinary study of carbohydrate-binding proteins (lectins), glycolipids and some other plant proteins that are capable of interacting with endogenous or foreign (macro) molecules.
- Track 7-1Lipid and lipoprotein metabolism
- Track 7-2Protein-lipid & lipid- lipid interactions
- Track 7-3Obesity and health
- Track 7-4Lipids in nutrition and health
- Track 7-5Structural diversity of lipids
Glycans are at the center of many disorders and diseases sparking the possibility of exploiting them for therapeutic and diagnostic purposes. There are many biochemical pathways and diseases in which glycans are intricately involved. Gaging the vast potential and the promise that glycobiology holds, many pharma and biotech companies have already started allocating their R&D budget to it. Presently, with our drug arsenal fast depleting against drug resistant and mutant pathogens, glycobiology hold an untapped source of new candidate drugs.
- Track 8-1 Glycoconjugate vaccines
- Track 8-2Glycoengineering of immunogens
- Track 8-3Biomarkers in drug design
- Track 8-4Screening and drug design
- Track 8-5Drug interaction in cellular networking
- Track 8-6Biodefense vaccine mechanism
Glycan sequences cannot be described by a simple linear one-letter code as each pair of monosaccharides can be linked in several ways and branched structures can be formed. Few of the bioinformatics algorithms developed for genomics or proteomics can be directly adapted for glycomics. The development of algorithms, which allow a rapid, automatic interpretation of mass spectra to identify glycan structures, is currently the most active field of research. The development and use of informatics tools and databases for glycobiology and glycomics research has increased considerably in recent years. In terms of bioinformatics in glycobiology, there are several paths of research that are currently in progress.
- Track 9-1Computational approaches in structural biology
- Track 9-2Structural biology In cancer research
- Track 9-3Recent advances in structural biology
- Track 9-4Data integration pathway analysis
- Track 9-5Data mining and data analysis
- Track 9-6Integrating gene expression and metabolomics data
Glycobiology along with the field of proteomics, particularly the application of mass spectrometry analysis to protein samples, is well-established and growing rapidly. Proteomics studies along with glycans generate large volumes of raw experimental data and inferred biological results. To facilitate the dissemination of these data, centralized data repositories have been developed that make the data and results accessible to proteomics researchers and biologists alike. Experimental analysis of proteomics data repositories focuses exclusively on freely-available, centralized data resources that disseminate or store experimental mass spectrometry data and results.
- Track 10-1Bioinformatics database
- Track 10-2Bioinformatics tools for protein analysis
- Track 10-3Algorithm and tools
- Track 10-4Protein sequencing
- Track 10-5Molecular interactions
- Track 10-63D Protein structure determination
Glycobiology is the study of the structure, biosynthesis and biology of saccharides that are widely distributed in nature. Sugars or saccharides are essential components of all living things and aspects of the various roles they play in biology and are researched in various medical, biochemical and biotechnological fields. The study of glycan structures is also complicated by the lack of a direct template for their biosynthesis, contrary to the case with proteins where their amino acid sequence is determined by their corresponding gene.
- Track 11-1Oligosaccharide synthesis
- Track 11-2Glycosaminoglycans
- Track 11-3Microarray gene expression
- Track 11-4Glycan immunotherapies
- Track 11-5Glycan sensing
- Track 11-6Glycan binding proteins
- Track 11-7Sugar structures
- Track 11-8Frontiers in glycoscience