Ming Zhang
University of Georgia, USA
Title: HIV Glycoprotein Reference for Influenza Vaccine Design
Biography
Biography: Ming Zhang
Abstract
N-linked glycosylation is a posttranslational modification that has significantly contributed to the rapid evolution of HIV-1. In particular, enrichment of N-linked glycosylation sites can be found within Envelope variable loops, regions that play an essential role in HIV pathogenesis and immunogenicity. In this presentation, I will describe some strategies we learned through though studies of HIV N-linked glycosylation, on both individual and population aspects, that can be implemented in virus vaccine designs, including for influenza prevention purposes.
