Glyco Biomarkers

Glycans can mediate a wide variety of biological roles by virtue of their mass, shape, charge, or other physical properties. However, many of their more specific biological roles are mediated via recognition by GBPs. Nature appears to have taken full advantage of the vast diversity of glycans expressed in organisms by evolving protein modules to recognize discrete glycans that mediate specific physiological or pathological processes. Excluding glycan-specific antibodies, GBPs broadly into two major groups such as lectins and glycosaminoglycan-binding proteins. Most lectins are members of families with defined “carbohydrate-recognition domains” (CRDs) that apparently evolved from shared ancestral genes, often retaining specific features of primary amino acid sequence or three-dimensional structure. Thus, new family members can be identified by searching protein sequence or structural databases. The natural ligands for most lectins are typically complex glycoconjugates that carry clustered arrays of the cognate carbohydrate or unique glycan structures, thus cooperating with clustered lectin-binding sites to generate high-avidity binding, which is further enhanced by mass transport effects (high local concentrations of ligands).

Relevant Conferences: Glycobiology Conferences Biochemistry Conferences

7th International Conference on Bioinformatics, October 24-26, 2016 Rome, Italy; International Conference on Structural Biology, August 22-23, 2016 New Orleans, USA; International Conference on Glycomics, December 01-02, 2016 Atlanta, Georgia, USA; International Conference on Nucleic Acids, August 04-05, 2016 New Orleans, Louisiana, USA; 2nd International Conference on Transcriptomics, September 12-14, 2016 Philadelphia, Pennsylvania, USA; International Conference on Obesity & Chronic Diseases, July 25-27, 2016 Las Vegas USA; International Conference on New Therapeutics for Diabetes and Obesity, April 17-20, 2016 La Jolla, USA; Conference on Plasma Spectrochemistry, January 10-16, 2016 Tucson, USA; Euro Fed Lipid Congress, September 18-21, 2016 Gent, Belgium; Conference on Obesity and Adipose Tissue Biology, February 15-19, 2016 Banff, Canada; Society for Glycobiology, November 19-22, 2016 New Orleans, Louisiana, USA; American Society for Biochemistry and Molecular Biology (ASBMB), April 02-06, 2016 San Diego, USA; Federation of American Societies for Experimental Biology (FASEB), June 12-17, 2016 Florida, USA

  • Glycosylation in therapeutics
  • Glycans in neuroscience
  • Vaccine development
  • Glyco medicine
  • Glyco lipid profiling
  • Glycan sensing

Related Conference of Glyco Biomarkers

June 26-28, 2017

3rd Glycobiology World Congress

London, UK
September 18-20, 2017

9th International Conference on Structural Biology

Zurich, Switzerland
September 21-22, 2017

International Conference on Glycobiology

Houston, Texas, USA
September 28-29, 2017

2nd International Conference on Biochemistry

Dubai, UAE
October 12-13, 2017

Global Proteomics Conference

Dubai, UAE
October 30 - November 01, 2017

3rd International Conference on Transcriptomics

Bangkok, Thailand
November 13-15, 2017

9th International Conference and Expo on Proteomics

Paris, France
November 13-14, 2017

9th International Conference on Bioinformatics

Paris, France
December 07-09, 2017

Biochemistry- 2017 (CME & CPD Accredited)

Frankfurt, Germany

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