Glycans in Genetic Disorders

Carbohydrates were prominent in the early history of immunology in defining the identity of antigens recognized by antibodies. In addition, the ability of antibodies to specifically recognize glycans was exploited in studies defining the size of the antigen-binding site. Nevertheless, for many decades following these early discoveries the broader potential importance of carbohydrates in both innate and adaptive immune responses was largely overlooked. However, times are changing and glycobiologists and immunologists are now collaborating extensively to explore this very fertile area of immunobiologyNumerous carbohydrate-binding proteins, or lectins, have been identified on the surfaces of immune cells. Interactions of lectins with glycans usually require several monosaccharide moieties presented in the correct conformation for high-affinity binding. Modification of proteins and lipids by glycosylation is a highly regulated process resulting in a diverse repertoire of glycan structures.

Glycans are at the center of many disorders and diseases sparking the possibility of exploiting them for therapeutic and diagnostic purposes. There are many biochemical pathways and diseases in which glycans are intricately involved. Gaging the vast potential and the promise that glycobiology holds, many pharma and biotech companies have already started allocating their R&D budget to it. Presently, with our drug arsenal fast depleting against drug resistant and mutant pathogens, glycobiology hold an untapped source of new candidate drugs.

Relevant Conferences: Glycobiology Conferences Biochemistry Conferences

7th International Conference on Bioinformatics, October 24-26, 2016 Rome, Italy; International Conference on Structural Biology, August 22-23, 2016 New Orleans, USA; International Conference on Glycomics, December 01-02, 2016 Atlanta, Georgia, USA; International Conference on Nucleic Acids, August 04-05, 2016 New Orleans, Louisiana, USA; 2nd International Conference on Transcriptomics, September 12-14, 2016 Philadelphia, Pennsylvania, USA; International Conference on Obesity & Chronic Diseases, July 25-27, 2016 Las Vegas USA; International Conference on New Therapeutics for Diabetes and Obesity, April 17-20, 2016 La Jolla, USA; Conference on Plasma Spectrochemistry, January 10-16, 2016 Tucson, USA; Euro Fed Lipid Congress, September 18-21, 2016 Gent, Belgium; Conference on Obesity and Adipose Tissue Biology, February 15-19, 2016 Banff, Canada; Society for Glycobiology, November 19-22, 2016 New Orleans, Louisiana, USA; American Society for Biochemistry and Molecular Biology (ASBMB), April 02-06, 2016 San Diego, USA; Federation of American Societies for Experimental Biology (FASEB), June 12-17, 2016 Florida, USA

  • Translational diagnostics
  • Tools and technologies for single cell analysis
  • The impact of genomic variation in clinical developmeni
  • Application and related disorders
  • Biochemical diagnostics

Related Conference of Glycans in Genetic Disorders

June 26-28, 2017

3rd Glycobiology World Congress

London, UK
September 18-20, 2017

9th International Conference on Structural Biology

Zurich, Switzerland
September 21-22, 2017

International Conference on Glycobiology

Houston, Texas, USA
September 28-29, 2017

2nd International Conference on Biochemistry

Dubai, UAE
October 12-13, 2017

Global Proteomics Conference

Dubai, UAE
October 30 - November 01, 2017

3rd International Conference on Transcriptomics

Bangkok, Thailand
November 13-15, 2017

9th International Conference and Expo on Proteomics

Paris, France
November 13-14, 2017

9th International Conference on Bioinformatics

Paris, France
December 07-09, 2017

Biochemistry- 2017 (CME & CPD Accredited)

Frankfurt, Germany

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